Bach2^tm2.1Igar
Targeted Allele Detail

Summary

• Symbol: Bach2^tm2.1Igar
• Name: BTB and CNC homology, basic leucine zipper transcription factor 2; targeted mutation 2.1, Kazuhiko Igarashi
• MGI ID: MGI:6116507
• Synonyms: Bach2 -RFP Bach2 -RFP Bach2-RFP, Bach2-td RFP
• Gene: Bach2 Location: Chr4:32238804-32586108 bp, + strand Genetic Position: Chr4, 14.02 cM, cytoband A4
• Alliance: Bach2^tm2.1Igar page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:254162
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: A cDNA encoding red fluorescent protein (td tomato) and an frt-flanked neomycin selection cassette was inserted into the start codon site. The neomycin selection cassette was removed by FLP1-mediated recombination. (J:254162)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bach2 Mutation: 43 strains or lines available

References

• Original: J:254162 Itoh-Nakadai A, et al., The transcription repressors Bach2 and Bach1 promote B cell development by repressing the myeloid program. Nat Immunol. 2014 Dec;15(12):1171-80
• All: 7 reference(s)