Reck^tm1.2Noda
Targeted Allele Detail

Summary

• Symbol: Reck^tm1.2Noda
• Name: reversion-inducing-cysteine-rich protein with kazal motifs; targeted mutation 1.2, Makoto Noda
• MGI ID: MGI:6116239
• Synonyms: Reck^deltaex2
• Gene: Reck Location: Chr4:43875530-43944806 bp, + strand Genetic Position: Chr4, 23.05 cM
• Alliance: Reck^tm1.2Noda page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:256044
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was floxed. The FRT flanked neo cassette used for ES cell selection was removed by flp mediated recombination. Cre-mediated mutation removed exon 2. (J:256044)

Expression

In Mice Carrying this Mutation:

21 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Reck Mutation: 46 strains or lines available

References

• Original: J:256044 Cho C, et al., Reck and Gpr124 Are Essential Receptor Cofactors for Wnt7a/Wnt7b-Specific Signaling in Mammalian CNS Angiogenesis and Blood-Brain Barrier Regulation. Neuron. 2017 Aug 30;95(5):1056-1073.e5
• All: 3 reference(s)