Vcpkmt^tm1.1Klng
Targeted Allele Detail

Summary

• Symbol: Vcpkmt^tm1.1Klng
• Name: valosin containing protein lysine (K) methyltransferase; targeted mutation 1.1, Arne Klungland
• MGI ID: MGI:6116233
• Gene: Vcpkmt Location: Chr12:69624402-69629884 bp, - strand Genetic Position: Chr12, 28.92 cM
• Alliance: Vcpkmt^tm1.1Klng page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:244368
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Undefined
• Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 4. Cre-mediated recombination removed exons 1 through 4 and the selection cassette. (J:244368)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vcpkmt Mutation: 10 strains or lines available

References

• Original: J:244368 Fusser M, et al., Lysine Methylation of the Valosin-Containing Protein (VCP) Is Dispensable for Development and Survival of Mice. PLoS One. 2015;10(11):e0141472
• All: 1 reference(s)