Rap1a^tm1.1Kina
Targeted Allele Detail

Summary

• Symbol: Rap1a^tm1.1Kina
• Name: Rap1a member of RAS oncogene family; targeted mutation 1.1, Tatsuo Kinashi
• MGI ID: MGI:6116229
• Gene: Rap1a Location: Chr3:105634583-105708652 bp, - strand Genetic Position: Chr3, 46.45 cM
• Alliance: Rap1a^tm1.1Kina page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:256602
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 4. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 4. Cre-mediated recombination removed exon 4. (J:256602)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rap1a Mutation: 23 strains or lines available

References

• Original: J:256602 Ueda Y, et al., Sema3e/Plexin D1 Modulates Immunological Synapse and Migration of Thymocytes by Rap1 Inhibition. J Immunol. 2016 Apr 1;196(7):3019-31
• All: 2 reference(s)