Tg(Eno2-BCL2)57Jcma
Transgene Detail

Summary

• Symbol: Tg(Eno2-BCL2)57Jcma
• Name: transgene insertion 57, Jean-Claude Martinou
• MGI ID: MGI:6115628
• Transgene: Tg(Eno2-BCL2)57Jcma Location: unknown
• Alliance: Tg(Eno2-BCL2)57Jcma page

Transgene origin

• Strain of Origin: (C57BL/6J x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Eno2-BCL2)57Jcma expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  BCL2 (596)

  Bcl2	(MGI:88138)

• Mutation details: The rat neuron-specific enolase (NSE) promoter drives expression of human BCL2. Six founders were obtained and lines 57, 71 and 73 were studied further. (J:133724)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:133724 Martinou JC, et al., Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia. Neuron. 1994 Oct;13(4):1017-30
• All: 3 reference(s)