Htr2a^tm1Pggd
Targeted Allele Detail

Summary

• Symbol: Htr2a^tm1Pggd
• Name: 5-hydroxytryptamine (serotonin) receptor 2A; targeted mutation 1, Paul Greengard
• MGI ID: MGI:6115614
• Synonyms: 5-HT2A KO
• Gene: Htr2a Location: Chr14:74878314-74944299 bp, + strand Genetic Position: Chr14, 39.37 cM
• Alliance: Htr2a^tm1Pggd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:256106
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Floxed mice were generated by introducing flanked loxP sites in the promoter and exon 1 of the gene. No further details are provided. (J:256106)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Htr2a Mutation: 45 strains or lines available

References

• Original: J:256106 Medrihan L, et al., Initiation of Behavioral Response to Antidepressants by Cholecystokinin Neurons of the Dentate Gyrus. Neuron. 2017 Aug 2;95(3):564-576.e4
• All: 1 reference(s)