Slc6a6^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Slc6a6^m1Btlr
• Name: solute carrier family 6 (neurotransmitter transporter, taurine), member 6; mutation 1, Bruce Beutler
• MGI ID: MGI:6113668
• Synonyms: durango
• Gene: Slc6a6 Location: Chr6:91661031-91736044 bp, + strand Genetic Position: Chr6, 40.73 cM
• Alliance: Slc6a6^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced G to A transition at base pair 91,723,471 (v38) on chromosome 6, or base pair 39,426 in the GenBank genomic region NC_000072. The mutation corresponds to residue 476 in the mRNA sequence NM_009320 within exon 4 of 6 total exons. The mutation results in a glycine (G) to aspartic acid (D) substitution at position 60 (G60D) in the protein. (J:254927)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc6a6 Mutation: 321 strains or lines available

References

• Original: J:254927 Ulfret-Vincenty R, et al., Mutagenetix entry for durango. MGI Direct Data Submission. 2018
• All: 1 reference(s)