Slc25a13^tm2.1Kjn
Targeted Allele Detail

Summary

• Symbol: Slc25a13^tm2.1Kjn
• Name: solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13; targeted mutation 2.1, Kenneth R Johnson
• MGI ID: MGI:6113313
• Gene: Slc25a13 Location: Chr6:6041218-6217173 bp, - strand Genetic Position: Chr6, 2.3 cM, cytoband A1
• Alliance: Slc25a13^tm2.1Kjn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:254776
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: exon 5 was replaced by a loxP flanked neomycin resistance cassette to generate a null allele and subsequent breeding to a Cre-deleter strain excised the neomycin resistance cassette to yield this null allele (J:254776)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc25a13 Mutation: 179 strains or lines available

References

• Original: J:254776 Johnson KR, et al., Deletion of a Long-Range Dlx5 Enhancer Disrupts Inner Ear Development in Mice. Genetics. 2018 Mar;208(3):1165-1179
• All: 1 reference(s)