Mirc20^tm2.1Blel
Targeted Allele Detail

Summary

• Symbol: Mirc20^tm2.1Blel
• Name: microRNA cluster 20, including Mir302b through Mir367; targeted mutation 2.1, Robert Blelloch
• MGI ID: MGI:6111935
• Synonyms: mir-302-eGFP
• Gene: Mirc20 Location: Chr3:127338877-127339456 bp Genetic Position: Chr3, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:247764
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An EGFP reporter gene with a floxed neomycin resistance gene was inserted downstream of the transcriptional start site of the cluster. Cre-mediated recombination removed the selection cassette. (J:247764)

Expression

In Mice Carrying this Mutation:

16 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc20 Mutation: 1 strain or line available

References

• Original: J:247764 Parchem RJ, et al., Two miRNA clusters reveal alternative paths in late-stage reprogramming. Cell Stem Cell. 2014 May 01;14(5):617-31
• All: 1 reference(s)