Mirc5^tm1.1Blel
Targeted Allele Detail

Summary

• Symbol: Mirc5^tm1.1Blel
• Name: microRNA cluster 5, including Mir290a through Mir295; targeted mutation 1.1, Robert Blelloch
• MGI ID: MGI:6111934
• Synonyms: mir-290-mCherry
• Gene: Mirc5 Location: unknown Genetic Position: Chr7, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:247764
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An mCherry reporter gene with a floxed neomycin resistance gene was inserted downstream of the transcriptional start site of the cluster. Cre-mediated recombination removed the selection cassette. (J:247764)

Expression

In Mice Carrying this Mutation:

81 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc5 Mutation: 2 strains or lines available

References

• Original: J:247764 Parchem RJ, et al., Two miRNA clusters reveal alternative paths in late-stage reprogramming. Cell Stem Cell. 2014 May 01;14(5):617-31
• All: 2 reference(s)