Gk5^m3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Gk5^m3Btlr
• Name: glycerol kinase 5; mutation 3, Bruce Beutler
• MGI ID: MGI:6111759
• Synonyms: tangyuan
• Gene: Gk5 Location: Chr9:96001415-96066661 bp, + strand Genetic Position: Chr9, 50.31 cM
• Alliance: Gk5^m3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a single nucleotide mutation to A of the second G (shown here in lower case)(96150797 bp on chr9; NCBI v38) in G-gTAAGTAGA (hyphen depicts exon-intron boundary). This mutation affects the exon 9-10 splice donor site. (J:243852)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gk5 Mutation: 44 strains or lines available

References

• Original: J:243852 Zhang D, et al., Skin-specific regulation of SREBP processing and lipid biosynthesis by glycerol kinase 5. Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5197-E5206
• All: 1 reference(s)