Gpr141b^{tm1(HBEGF)Ciphe}
Targeted Allele Detail

Summary

• Symbol: Gpr141b^{tm1(HBEGF)Ciphe}
• Name: G protein-coupled receptor 141B; targeted mutation 1, Centre d'ImmunoPhenomique
• MGI ID: MGI:6110580
• Synonyms: Gp141b^tm1Ciphe, Karma, Karma-tdTomato-hDTR
• Gene: Gpr141b Location: Chr13:19911596-19917121 bp, - strand Genetic Position: Chr13, 7.03 cM
• Alliance: Gpr141b^{tm1(HBEGF)Ciphe} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:232586
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, No functional change, Reporter)
• Mutation: Insertion
• Gpr141b^{tm1(HBEGF)Ciphe} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  HBEGF (1839)

  Hbegf

  (MGI:96070)

• Mutation details: The targeting construct introduced into the 3'UTR an IRES sequence, tdTomato reporter gene, 2A sequence and human diphtheria toxin receptor. (J:232586)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr141b Mutation: 20 strains or lines available

References

• Original: J:232586 Alexandre YO, et al., XCR1+ dendritic cells promote memory CD8+ T cell recall upon secondary infections with Listeria monocytogenes or certain viruses. J Exp Med. 2016 Jan 11;213(1):75-92
• All: 5 reference(s)