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Tg(CAG-Calr)#Mlk
Transgene Detail
Summary
Symbol: Tg(CAG-Calr)#Mlk
Name: transgene insertion, Marek Michalak
MGI ID: MGI:6108898
Synonyms: CRT-TG
Transgene: Tg(CAG-Calr)#Mlk  Location: unknown  
Alliance: Tg(CAG-Calr)#Mlk page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Conditional ready, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CAG-Calr)#Mlk expresses 1 gene
 
Mutation detailsThe transgene consists of the cytomegalovirus early enhancer/chicken beta-actin promoter, a loxP flanked chloramphenicol acetyltransferase (cat) gene followed by cDNA encoding HA-tagged mouse calreticulin. Cre mediated recombination results in excision of the cat gene and subsequent production of calreticulin. (J:199413)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:199413 Lee D, et al., Calreticulin induces dilated cardiomyopathy. PLoS One. 2013;8(2):e56387
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/24/2023
MGI 6.22
The Jackson Laboratory