Arl13b^tm1.1Tc
Targeted Allele Detail

Summary

• Symbol: Arl13b^tm1.1Tc
• Name: ADP-ribosylation factor-like 13B; targeted mutation 1.1, Tamara Caspary
• MGI ID: MGI:6107225
• Synonyms: Arl13b^floxed
• Gene: Arl13b Location: Chr16:62614048-62667403 bp, - strand Genetic Position: Chr16, 36.43 cM, cytoband C1.2
• Alliance: Arl13b^tm1.1Tc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: HZ2.2 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A targeting vector containing a loxP site and FRT site flanked PGK-puro deltaTK selection (pFlexible) cassette was inserted downstream of exon 2 of the targeted gene, and another loxP site was inserted upstream of exon 2. FLP-mediated recombination removed the neo cassette. (J:188997)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Arl13b Mutation: 22 strains or lines available

References

• Original: J:188997 Su CY, et al., Temporal deletion of Arl13b reveals that a mispatterned neural tube corrects cell fate over time. Development. 2012 Nov;139(21):4062-71
• All: 8 reference(s)