Meis1^tm1.2Rygo
Targeted Allele Detail

Summary

• Symbol: Meis1^tm1.2Rygo
• Name: Meis homeobox 1; targeted mutation 1.2, Ryo Goitsuka
• MGI ID: MGI:6101518
• Synonyms: Meis1^delta
• Gene: Meis1 Location: Chr11:18830428-18968992 bp, - strand Genetic Position: Chr11, 11.11 cM
• Alliance: Meis1^tm1.2Rygo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:250017
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 8 was deleted via Cre-mediated recombination of flanking loxP sites. (J:250017)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Meis1 Mutation: 46 strains or lines available

References

• Original: J:250017 Ariki R, et al., Homeodomain transcription factor Meis1 is a critical regulator of adult bone marrow hematopoiesis. PLoS One. 2014;9(2):e87646
• All: 1 reference(s)