Tg(CAG-Bmi1,-EGFP)IB5Mro
Transgene Detail

Summary

• Symbol: Tg(CAG-Bmi1,-EGFP)IB5Mro
• Name: transgene insertion IB5, Silvia Marino
• MGI ID: MGI:6101426
• Synonyms: STOPFloxBmi1
• Transgene: Tg(CAG-Bmi1,-EGFP)IB5Mro Location: unknown
• Alliance: Tg(CAG-Bmi1,-EGFP)IB5Mro page

Transgene origin

• Germline Transmission: Earliest citation of germline transmission: J:168826
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Transgene description

• Transgene Type: Transgenic (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: The CMV enhancer/chicken beta actin promoter (CAG) drives expression of a floxed betageo (a LacZ neomycin fusion) reporter, a full-length murine cDNA and an IRES-EGFP reporter. Clone IB5 was used to generate a line. (J:168826)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:168826 Yadirgi G, et al., Conditional activation of Bmi1 expression regulates self-renewal, apoptosis, and differentiation of neural stem/progenitor cells in vitro and in vivo. Stem Cells. 2011 Apr;29(4):700-12
• All: 2 reference(s)