Ttll7^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ttll7^em1(IMPC)J
• Name: tubulin tyrosine ligase-like family, member 7; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:6101191
• Gene: Ttll7 Location: Chr3:146558122-146689764 bp, + strand Genetic Position: Chr3, 72.28 cM, cytoband H3
• Alliance: Ttll7^em1(IMPC)J page
• IMPC: Ttll7 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory using Cas9 and guides with spacer sequences ACACCTTAAGATGAGTGACA, ACAGTGTTCCAGGTGCAGAC, CAAAACACAGCACTTGCAGA, and CCAGCGAGCAACGAGACAGG that targeted exon(s) ENSMUSE00000224812.5. This resulted in deletion(s) of 5 bp (location: Chr3:146602114-146602118; GRCm39), 500 bp (location: Chr3:146602257-146602756; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ttll7 Mutation: 40 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)