Esyt1^tm1.2Sud
Targeted Allele Detail

Summary

• Symbol: Esyt1^tm1.2Sud
• Name: extended synaptotagmin-like protein 1; targeted mutation 1.2, Thomas C Sudhof
• MGI ID: MGI:6101169
• Synonyms: 1KO
• Gene: Esyt1 Location: Chr10:128346117-128361728 bp, - strand Genetic Position: Chr10, 76.85 cM
• Alliance: Esyt1^tm1.2Sud page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:236019
• Parent Cell Line: ART B6-3, B6-3 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Cre-mediated recombination of Esyt1 resulted in the removal of the loxP-flanked exon 10, resulting in a null allele. (J:236019)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Esyt1 Mutation: 48 strains or lines available

References

• Original: J:236019 Sclip A, et al., Extended Synaptotagmin (ESyt) Triple Knock-Out Mice Are Viable and Fertile without Obvious Endoplasmic Reticulum Dysfunction. PLoS One. 2016;11(6):e0158295
• All: 1 reference(s)