Camkk1^tm1.1Arm
Targeted Allele Detail

Summary

• Symbol: Camkk1^tm1.1Arm
• Name: calcium/calmodulin-dependent protein kinase kinase 1, alpha; targeted mutation 1.1, Anthony R Means
• MGI ID: MGI:6099028
• Gene: Camkk1 Location: Chr11:72909834-72932899 bp, + strand Genetic Position: Chr11, 45.12 cM
• Alliance: Camkk1^tm1.1Arm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:248606
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exons 2 - 8 of the gene were flanked by loxP sites. Cre-mediated recombination in ES cells prior to mouse production resulted in a deletion of the loxP-flanked region. (J:248606)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Camkk1 Mutation: 20 strains or lines available

References

• Original: J:248606 Racioppi L, et al., Calcium/calmodulin-dependent protein kinase kinase 2 regulates macrophage-mediated inflammatory responses. J Biol Chem. 2012 Mar 30;287(14):11579-91
• All: 1 reference(s)