Tg(lacZ)180Kng
Transgene Detail

Summary

• Symbol: Tg(lacZ)180Kng
• Name: transgene insertion 180, David M Kingsley
• MGI ID: MGI:6098718
• Synonyms: IRE-lacZ, Ph7-lacZ
• Transgene: Tg(lacZ)180Kng Location: unknown
• Alliance: Tg(lacZ)180Kng page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgene construct contains a Phage VII (Ph7/IRE) segment of DNA (derived from a regulatory region approximately 17.9 kb clone downstream of the Bmp5 coding sequences), and an Hsp68 (Hspa1b) minimal promoter-lacZ-SV40-pA reporter cassette. During embryonic development (E15.5 dpc), the transgene is expressed in several sites including the tips of the developing nasal turbinates and the thyroid cartilage. In adults, the transgene is expressed in multiple tissues following injury, including bone, skin and lung. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:60643 DiLeone RJ, et al., Efficient studies of long-distance Bmp5 gene regulation using bacterial artificial chromosomes. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1612-7
• All: 2 reference(s)