Tg(CAG-Atoh1,-lacZ)#Haoz
Transgene Detail

Summary

• Symbol: Tg(CAG-Atoh1,-lacZ)#Haoz
• Name: transgene insertion, Haotian Zhao
• MGI ID: MGI:5925318
• Synonyms: CAG-A1Z
• Transgene: Tg(CAG-Atoh1,-lacZ)#Haoz Location: unknown
• Alliance: Tg(CAG-Atoh1,-lacZ)#Haoz page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: The transgenic construct comprises the following elements: CAG promoter, a loxP site flanked STOP cassette, the mouse gene, an IRES site, the beta-galactosidase (lacZ) reporter gene, and poly(A) features. The inserted mouse gene and the reporter gene will only be expressed after removal of the STOP cassette through cre-mediated recombination. The pound # sign is used in the symbol where no line is specified. (J:243119)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:243119 Grausam KB, et al., ATOH1 Promotes Leptomeningeal Dissemination and Metastasis of Sonic Hedgehog Subgroup Medulloblastomas. Cancer Res. 2017 Jul 15;77(14):3766-3777
• All: 1 reference(s)