Tg(CAG-cat,-Prkaa1)#Mhzo
Transgene Detail

Summary

• Symbol: Tg(CAG-cat,-Prkaa1)#Mhzo
• Name: transgene insertion, Ming-Hui Zou
• MGI ID: MGI:5919974
• Transgene: Tg(CAG-cat,-Prkaa1)#Mhzo Location: unknown
• Alliance: Tg(CAG-cat,-Prkaa1)#Mhzo page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-cat,-Prkaa1)#Mhzo expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Prkaa1 (MGI:2145955)

• Mutation details: The construct consists of the mouse gene inserted downstream of the CAG promoter and a loxP site flanked chloramphenicol acetyltransferace gene. The cat gene blocks the expression of the mouse gene. The mouse gene is expressed only after removal of the cat gene through cre-mediated recombination. The pound # sign is used in the symbol because no line was specified. (J:242770)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:242770 Zhang M, et al., AMP-activated protein kinase alpha1 promotes atherogenesis by increasing monocyte-to-macrophage differentiation. J Biol Chem. 2017 May 12;292(19):7888-7903
• All: 1 reference(s)