Ythdf2tm1.1Doca
Targeted Allele Detail
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Symbol: |
Ythdf2tm1.1Doca |
Name: |
YTH N6-methyladenosine RNA binding protein 2; targeted mutation 1.1, Donal OCarroll |
MGI ID: |
MGI:5911733 |
Synonyms: |
Ythdf2HA-FL |
Gene: |
Ythdf2 Location: Chr4:131912227-131939567 bp, - strand Genetic Position: Chr4, 64.92 cM
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Alliance: |
Ythdf2tm1.1Doca page
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Germline Transmission: |
Earliest citation of germline transmission:
J:243747
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, Epitope tag, No functional change, Reporter) |
Mutation: |
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Insertion
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Mutation details: A cassette containing an EGFP reporter gene, PreScission protease cleavage site and several epitope tags (6 histidine, FLAG and 2 HA) was inserted into exon 1 at the ATG start site. Exon 2 was flanked by loxP sites. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted upstream of exon 2.
(J:243747)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ythdf2 Mutation: |
30 strains or lines available
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Original: |
J:243747 Ivanova I, et al., The RNA m6A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence. Mol Cell. 2017 Sep 21;67(6):1059-1067.e4 |
All: |
4 reference(s) |
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