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Targeted Allele Detail
Symbol: Mglltm1.2Rzim
Name: monoglyceride lipase; targeted mutation 1.2, Robert Zimmermann
MGI ID: MGI:5911442
Gene: Mgll  Location: Chr6:88701397-88805342 bp, + strand  Genetic Position: Chr6, 39.51 cM
Alliance: Mglltm1.2Rzim page
Germline Transmission:  Earliest citation of germline transmission: J:228956
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprt1b-m3
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
Mutation detailsA floxed neo cassette was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 4. Cre-mediated recombination removed the neo cassette leaving exons 3 and 4 floxed. (J:172679, J:228956)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mgll Mutation:  29 strains or lines available
Original:  J:228956 Grabner GF, et al., Deletion of Monoglyceride Lipase in Astrocytes Attenuates Lipopolysaccharide-induced Neuroinflammation. J Biol Chem. 2016 Jan 8;291(2):913-23
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.24
The Jackson Laboratory