Rack1^tm1Jyz
Targeted Allele Detail

Summary

• Symbol: Rack1^tm1Jyz
• Name: receptor for activated C kinase 1; targeted mutation 1, Jiyan Zhang
• MGI ID: MGI:5911420
• Synonyms: Gnb2l1^F
• Gene: Rack1 Location: Chr11:48691187-48697068 bp, + strand Genetic Position: Chr11, 28.77 cM
• Alliance: Rack1^tm1Jyz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:228961
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: An FRT flanked neo cassette and loxP site were inserted in intron 1 and a loxP site was inserted in intron 2 via homologous recombination. (J:228961)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rack1 Mutation: 55 strains or lines available

References

• Original: J:228961 Zhao Y, et al., RACK1 Promotes Autophagy by Enhancing the Atg14L-Beclin 1-Vps34-Vps15 Complex Formation upon Phosphorylation by AMPK. Cell Rep. 2015 Nov 17;13(7):1407-17
• All: 4 reference(s)