Del(9Cd3g-Cd3e)1Csk
Targeted Allele Detail

Summary

• Symbol: Del(9Cd3g-Cd3e)1Csk
• Name: deletion, Chr 9, Chugai Pharmaceutical Co, Ltd; deletion, Chr 9, Chugai Pharmaceutical Co, Ltd 1
• MGI ID: MGI:5910028
• Synonyms: Del1Csk, mCd3 edg^-
• Gene: Del(9Cd3g-Cd3e)1Csk Location: unknown Genetic Position: Chr9, Syntenic

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion, Intragenic deletion
• Del(9Cd3g-Cd3e)1Csk involves 3 genes/genome features (Cd3g, Cd3d, Cd3e) View all
• Mutation details: A neomycin resistance cassette with a 5' loxP site was inserted upstream of Cd3e. A Rox-flanked hygromycin resistance cassette with a 5' loxP site was inserted downstream of Cd3g. Cre- and Dre-mediated recombination removed Cd3e, Cd3d and Cd3g along with both selection cassettes. (J:243702)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(9Cd3g-Cd3e)1Csk Mutation: 0 strains or lines available

References

• Original: J:243702 Ueda O, et al., Entire CD3epsilon, delta, and gamma humanized mouse to evaluate human CD3-mediated therapeutics. Sci Rep. 2017 Apr 03;7:45839
• All: 1 reference(s)