Tg(Tcra5B6,Tcrb5B6)1858Kuch
Transgene Detail

Summary

• Symbol: Tg(Tcra5B6,Tcrb5B6)1858Kuch
• Name: transgene insertion 1858, Vijay Kuchroo
• MGI ID: MGI:5909279
• Transgene: Tg(Tcra5B6,Tcrb5B6)1858Kuch Location: unknown
• Alliance: Tg(Tcra5B6,Tcrb5B6)1858Kuch page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The transgene contains a pre-arranged Tcr locus from the T cell clone 5B6 (Valpha4Jalpha8,Vbeta6Dbeta2Jbeta2.6), which recognizes the PLP-139-151 epitope. Line 1858 was generated. (J:177335)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:177335 Waldner H, et al., Fulminant spontaneous autoimmunity of the central nervous system in mice transgenic for the myelin proteolipid protein-specific T cell receptor. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3412-7
• All: 7 reference(s)