Tg(TcraB16.3,TcrbB16.3)AMcd
Transgene Detail

Summary

• Symbol: Tg(TcraB16.3,TcrbB16.3)AMcd
• Name: transgene insertion A, Hugh O McDevitt
• MGI ID: MGI:5909255
• Synonyms: B16.3, Valpha4.5-Jalpha6 and Vbeta1-Jbeta2.7
• Transgene: Tg(TcraB16.3,TcrbB16.3)AMcd Location: unknown
• Alliance: Tg(TcraB16.3,TcrbB16.3)AMcd page

Transgene origin

• Strain of Origin: NOD

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The transgene contains the prearranged Tcr recognizing the peptide epitope 286-300 (p286) of GAD2 (p286) from the hydridoma cell line B16.3 (Valpha4.5-Jalpha6 and Vbeta1-Jbeta2.7). Lines A and B were generated with line A selected the representative line. (J:78642)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:78642 Tarbell KV, et al., CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer. J Exp Med. 2002 Aug 19;196(4):481-92
• All: 3 reference(s)