Il18r1^tm1.1Flv
Targeted Allele Detail

Summary

• Symbol: Il18r1^tm1.1Flv
• Name: interleukin 18 receptor 1; targeted mutation 1.1, Richard A Flavell
• MGI ID: MGI:5908107
• Gene: Il18r1 Location: Chr1:40504712-40540014 bp, + strand Genetic Position: Chr1, 19.27 cM, cytoband B
• Alliance: Il18r1^tm1.1Flv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:227990
• Parent Cell Line: JM8 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 3 was floxed and FRT flanked neo cassette was inserted via homologous recombination. Flp mediated recombination removed the neo cassette. (J:227990)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il18r1 Mutation: 44 strains or lines available

References

• Original: J:227990 Nowarski R, et al., Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis. Cell. 2015 Dec 3;163(6):1444-56
• All: 7 reference(s)