Eomes^tm1Gtbz
Targeted Allele Detail

Summary

• Symbol: Eomes^tm1Gtbz
• Name: eomesodermin; targeted mutation 1, Gabrielle T Belz
• MGI ID: MGI:5907979
• Synonyms: Eomes^mCherry, Eomes^tm1Csei
• Gene: Eomes Location: Chr9:118307259-118315176 bp, + strand Genetic Position: Chr9, 70.21 cM, cytoband F3
• Alliance: Eomes^tm1Gtbz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:227909
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: A loxP site and FRT flanked IRES-mCherry-neo cassette were inserted in intron 3 via homologous recombination. The original targeting vector had a loxP site in intron 1 but this is not present in this allele. (J:227909)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eomes Mutation: 42 strains or lines available

References

• Original: J:227909 Kara EE, et al., CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells. Nat Commun. 2015;6:8644
• All: 5 reference(s)