Tert^tm3.1Sear
Targeted Allele Detail

Summary

• Symbol: Tert^tm3.1Sear
• Name: telomerase reverse transcriptase; targeted mutation 3.1, Steven E Artand
• MGI ID: MGI:5907326
• Synonyms: Tert^Tomato
• Gene: Tert Location: Chr13:73775030-73797962 bp, + strand Genetic Position: Chr13, 40.12 cM
• Alliance: Tert^tm3.1Sear page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:227119
• Parent Cell Line: JM8.F6 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: A tdTomato-polyA cassette was inserted just after the initiation codon and a floxed puro cassette was inserted in intron 1 via homologous recombination. Cre mediated recombination removed the puro cassette. (J:227119)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tert Mutation: 55 strains or lines available

References

• Original: J:227119 Pech MF, et al., High telomerase is a hallmark of undifferentiated spermatogonia and is required for maintenance of male germline stem cells. Genes Dev. 2015 Dec 1;29(23):2420-34
• All: 2 reference(s)