Tg(Myh6/tetO-TGFBI)1Jmol
Transgene Detail

Summary

• Symbol: Tg(Myh6/tetO-TGFBI)1Jmol
• Name: transgene insertion 1, Jeffery D Molkentin
• MGI ID: MGI:5906602
• Transgene: Tg(Myh6/tetO-TGFBI)1Jmol Location: unknown
• Alliance: Tg(Myh6/tetO-TGFBI)1Jmol page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(Myh6/tetO-TGFBI)1Jmol expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TGFB1 (7040)

  Tgfb1

  (MGI:98725)

• Mutation details: Human TGFBI cDNA was placed under the regulatory control of a modified tetracycline-responsive promoter element (tetO) fused to the cardiac-specific alpha myosin heavy chain (Myh6) mouse promoter. (J:242822)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:242822 Schwanekamp JA, et al., TGFBI functions similar to periostin but is uniquely dispensable during cardiac injury. PLoS One. 2017;12(7):e0181945
• All: 1 reference(s)