Map3k20^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Map3k20^em1(IMPC)J
• Name: mitogen-activated protein kinase kinase kinase 20; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:5906321
• Gene: Map3k20 Location: Chr2:72115981-72272954 bp, + strand Genetic Position: Chr2, 43.11 cM
• Alliance: Map3k20^em1(IMPC)J page
• IMPC: Map3k20 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory using Cas9 and guides with spacer sequences CATGACGCCATACTTTTCTT, CTTAGCACCAAAGAAAAGTA, TGCAGAGCCTGACCAGCGCG, and TTGTAGGACAGATTAGCTCG that targeted exon(s) ENSMUSE00001216817.2 ENSMUSE00001293997.2. This resulted in deletion(s) of 609 bp (location: Chr2:72202004-72202612; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Map3k20 Mutation: 67 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 4 reference(s)