Tg(Col2a1-d2EGFP)1Waho
Transgene Detail
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Symbol: |
Tg(Col2a1-d2EGFP)1Waho |
Name: |
transgene insertion 1, William A Horton |
MGI ID: |
MGI:5904769 |
Synonyms: |
Tg(Col2a1-EGFP*)1Waho |
Transgene: |
Tg(Col2a1-d2EGFP)1Waho Location: unknown
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Alliance: |
Tg(Col2a1-d2EGFP)1Waho page
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Strain of Origin: |
(C57BL/6 x SJL)F2
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Transgene Type: |
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Transgenic (Reporter) |
Mutation: |
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Insertion
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Mutation details: A construct in which the mouse Col2a1 promoter/enhancer drives expression of d2EGFP was injected into C57BL/6 x SJL F2 embryos. d2EGFP, derived from plasmid pd2EGFP-N1, carries a modification of EGFP in which residues 422-461 of mouse ornithine decarboxylase (MODC) are fused to the C-terminus of EGFP. This modification creates a destabilized, red-shifted variant of the wildtype GFP which has been optimized for brighter fluorescence and higher expression in mammalian cells.
(J:169056)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:169056 Tryfonidou MA, et al., Novel type II collagen reporter mice: New tool for assessing collagen 2alpha1 expression in vivo and in vitro. Dev Dyn. 2011 Mar;240(3):663-73 |
All: |
2 reference(s) |
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