Arf4^tm1Gjp
Targeted Allele Detail

Summary

• Symbol: Arf4^tm1Gjp
• Name: ARF GTPase 4; targeted mutation 1, Gregory Pazour
• MGI ID: MGI:5902137
• Synonyms: Arf4^flox
• Gene: Arf4 Location: Chr14:26359289-26377997 bp, + strand Genetic Position: Chr14, 16.09 cM
• Alliance: Arf4^tm1Gjp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:241418
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting vector is designed to include a neomycin selection cassette, followed by a loxP site, inserted downstream of exon 3, and another loxP site inserted upstream of exon 2. (J:241418)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Arf4 Mutation: 20 strains or lines available

References

• Original: J:241418 Pearring JN, et al., Loss of Arf4 causes severe degeneration of the exocrine pancreas but not cystic kidney disease or retinal degeneration. PLoS Genet. 2017 Apr;13(4):e1006740
• All: 1 reference(s)