Ola1^tm1.2Zshi
Targeted Allele Detail

Summary

• Symbol: Ola1^tm1.2Zshi
• Name: Obg-like ATPase 1; targeted mutation 1.2, Zheng-Zheng Shi
• MGI ID: MGI:5898257
• Gene: Ola1 Location: Chr2:72923145-73044791 bp, - strand Genetic Position: Chr2, 43.35 cM, cytoband C3
• Alliance: Ola1^tm1.2Zshi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:236306
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to insert a single loxP site upstream of exon 2, and an FRT-flanked neomycin resistance (neo) cassette, followed by a second loxP site, downstream of exon 2 of the gene. Recombinase mediated recombination removed the FRT-flanked neo cassette and exon 2. (J:236306)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ola1 Mutation: 31 strains or lines available

References

• Original: J:236306 Ding Z, et al., OLA1, a Translational Regulator of p21, Maintains Optimal Cell Proliferation Necessary for Developmental Progression. Mol Cell Biol. 2016 Oct 15;36(20):2568-82
• All: 1 reference(s)