Tg(Foxp3-RFP,-cre)1Narl
Transgene Detail

Summary

• Symbol: Tg(Foxp3-RFP,-cre)1Narl
• Name: transgene insertion 1, National Applied Research Laboratories
• MGI ID: MGI:5898001
• Transgene: Tg(Foxp3-RFP,-cre)1Narl Location: unknown
• Alliance: Tg(Foxp3-RFP,-cre)1Narl page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Recombinase, Reporter)
• Mutation: Insertion
• Tg(Foxp3-RFP,-cre)1Narl expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Foxp3

• Mutation details: The Foxp3 promoter drives the expression of Red Fluorescent Protein (RFP) and Cre recombinase. RFP expression is detected in CD4+CD25+ cells. Cre activity is observed in thymus, Peyer's patch, lymph nodes of neck, iliac and mesentery, spleen, lung, small intestine, appendix, testis, epidiymis, and brown fat. (J:221795)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Foxp3 (species not specified) Summary of all recombinase alleles driven by Foxp3.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:221795 Hsiao HW, et al., Deltex1 antagonizes HIF-1alpha and sustains the stability of regulatory T cells in vivo. Nat Commun. 2015;6:6353
• All: 2 reference(s)