Ccl20^{tm1c(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: Ccl20^{tm1c(EUCOMM)Hmgu}
• Name: C-C motif chemokine ligand 20; targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:5892151
• Gene: Ccl20 Location: Chr1:83094487-83096888 bp, + strand Genetic Position: Chr1, 42.69 cM
• Alliance: Ccl20^{tm1c(EUCOMM)Hmgu} page
• IMPC: Ccl20 gene page

Mutation origin

• Mutant Cell Line: HEPD0887_2_G12
• Germline Transmission: Earliest citation of germline transmission: J:240732
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion Vector: L1L2_Bact_P
• Mutation details: FLP-mediated recombination in the parental Ccl20^{tm1a(EUCOMM)Hmgu} allele resulted in the removal of the promoter-driven neomycin selection cassette and the beta-galactosidase gene leaving exon 2 flanked with loxP sites. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:240732)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ccl20 Mutation: 22 strains or lines available

References

• Original: J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015
• All: 2 reference(s)