Otx2^tm4.1Tlam
Targeted Allele Detail

Summary

• Symbol: Otx2^tm4.1Tlam
• Name: orthodenticle homeobox 2; targeted mutation 4.1, Thomas Lamonerie
• MGI ID: MGI:5888988
• Synonyms: Otx2^CTAP-tag
• Gene: Otx2 Location: Chr14:48894238-48905101 bp, - strand Genetic Position: Chr14, 25.36 cM
• Alliance: Otx2^tm4.1Tlam page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:227649
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutation: Insertion
• Mutation details: The targeting construct introduced into the C-terminus at a modified stop codon a sequence designed for tandem-affinity protein purification (TAP-tag) sequence. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted downstream of the tag. (J:227649)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Otx2 Mutation: 51 strains or lines available

References

• Original: J:227649 Fant B, et al., Comprehensive interactome of Otx2 in the adult mouse neural retina. Genesis. 2015 Nov;53(11):685-94
• All: 1 reference(s)