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Nraddtm1.1Pabk
Targeted Allele Detail
Summary
Symbol: Nraddtm1.1Pabk
Name: neurotrophin receptor associated death domain; targeted mutation 1.1, Philip A Barker
MGI ID: MGI:5888870
Synonyms: Nraddflox
Gene: Nradd  Location: Chr9:110450203-110453461 bp, - strand  Genetic Position: Chr9, 60.26 cM, cytoband F2
Alliance: Nraddtm1.1Pabk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:237623
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsLoxP sites were inserted to flank exon 2. A frt-flanked neomycin selection cassette was removed via Flp-mediated recombination to generate the conditional allele. (J:237623)
Generation of the Nraddtm1.1Pabk and Nraddtm1.2Pabk alleles
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nradd Mutation:  24 strains or lines available
References
Original:  J:237623 Unsain N, et al., Generation and characterization of mice bearing null alleles of nradd/Nrh2. Genesis. 2016 Dec;54(12):605-612
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory