Mmp14^tm1.1Pzig
Targeted Allele Detail

Summary

• Symbol: Mmp14^tm1.1Pzig
• Name: matrix metallopeptidase 14 (membrane-inserted); targeted mutation 1.1, Paola Zigrino
• MGI ID: MGI:5888864
• Gene: Mmp14 Location: Chr14:54669055-54679913 bp, + strand Genetic Position: Chr14, 27.79 cM
• Alliance: Mmp14^tm1.1Pzig page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:240452
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 2 through 4 were floxed. Flp-mediated recombination removed the selection cassette inserted upstream of exon 2. (J:240452)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mmp14 Mutation: 42 strains or lines available

References

• Original: J:240452 Zigrino P, et al., Loss of epidermal MMP-14 expression interferes with angiogenesis but not with re-epithelialization. Eur J Cell Biol. 2012 Oct;91(10):748-56
• All: 3 reference(s)