Tgfbi^tm1Nap
Targeted Allele Detail

Summary

• Symbol: Tgfbi^tm1Nap
• Name: transforming growth factor, beta induced; targeted mutation 1, Nathalie Allaman-Pillet
• MGI ID: MGI:5882686
• Synonyms: Bigh3^lox
• Gene: Tgfbi Location: Chr13:56757399-56787172 bp, + strand Genetic Position: Chr13, 30.09 cM, cytoband B-C1
• Alliance: Tgfbi^tm1Nap page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:230754
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 1. (J:230754)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tgfbi Mutation: 39 strains or lines available

References

• Original: J:230754 Allaman-Pillet N, et al., Tgfbi/Bigh3 silencing activates ERK in mouse retina. Exp Eye Res. 2015 Nov;140:159-70
• All: 1 reference(s)