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Slc44a2tm1.1Tec
Targeted Allele Detail
Summary
Symbol: Slc44a2tm1.1Tec
Name: solute carrier family 44, member 2; targeted mutation 1.1, Thomas E Carey
MGI ID: MGI:5828929
Synonyms: Slc44a2flox
Gene: Slc44a2  Location: Chr9:21232015-21266324 bp, + strand  Genetic Position: Chr9, 7.77 cM
Alliance: Slc44a2tm1.1Tec page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:239440
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA targeting vector containing an FRT-flanked PGK-Neo selection cassette followed by a loxP site inserted upstream of exon 3 and another loxP site was inserted downstream of exon 10. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exons 3 through 10 floxed. (J:239440)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc44a2 Mutation:  48 strains or lines available
References
Original:  J:239440 Kommareddi P, et al., Hair Cell Loss, Spiral Ganglion Degeneration, and Progressive Sensorineural Hearing Loss in Mice with Targeted Deletion of Slc44a2/Ctl2. J Assoc Res Otolaryngol. 2015 Dec;16(6):695-712
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory