Tg(TLR10)5-1Tapp
Transgene Detail

Summary

• Symbol: Tg(TLR10)5-1Tapp
• Name: transgene insertion 5-1, Richard Tapping
• MGI ID: MGI:5828827
• Transgene: Tg(TLR10)5-1Tapp Location: unknown
• Alliance: Tg(TLR10)5-1Tapp page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(TLR10)5-1Tapp expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  human	TLR10 (81793)

• Tg(TLR10)5-1Tapp expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  human	TLR10 (81793)

• Mutation details: The transgenic construct consists of a human RPCI-11 BAC clone #1148D18 containing the entire TLR10 gene (and approximately 4 kb of the upstream and approximately 3 kb of the downstream flanking sequence). (J:239438)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:239438 Hess NJ, et al., TLR10 Is a B Cell Intrinsic Suppressor of Adaptive Immune Responses. J Immunol. 2017 Jan 15;198(2):699-707
• All: 1 reference(s)