Trib1^tm1.1Mrl
Targeted Allele Detail

Summary

• Symbol: Trib1^tm1.1Mrl
• Name: tribbles pseudokinase 1; targeted mutation 1.1, Merck Research Laboratory
• MGI ID: MGI:5828745
• Synonyms: Trib1_fl
• Gene: Trib1 Location: Chr15:59520503-59528948 bp, + strand Genetic Position: Chr15, 25.41 cM
• Alliance: Trib1^tm1.1Mrl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:226409
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exon 2 was floxed. Flp-mediated recombination removed the selection cassette. (J:226409)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trib1 Mutation: 24 strains or lines available

Notes

More details can be found at http://www.taconic.com/10265.

References

• Original: J:226409 Bauer RC, et al., Tribbles-1 regulates hepatic lipogenesis through posttranscriptional regulation of C/EBPalpha. J Clin Invest. 2015 Oct 1;125(10):3809-18
• All: 5 reference(s)