Gt(ROSA)26Sor^{tm1(Hbegf)Lgc}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(Hbegf)Lgc}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Lloyd G Cantley
• MGI ID: MGI:5828135
• Synonyms: Rosa-DTR^flox, Terminator
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(Hbegf)Lgc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:235558
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(Hbegf)Lgc} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Hbegf

• Mutation details: The targeting construct introduced into the locus a splice acceptor, loxP site, diphtheria toxin receptor (DTR or Hbegf), polyadenylation sequence, loxP site, neomycin resistance cassette, loxP site, IRES sequence, GFP reporter gene and polyadenylation sequence. (J:235558)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:235558 Guo JK, et al., The Terminator mouse is a diphtheria toxin-receptor knock-in mouse strain for rapid and efficient enrichment of desired cell lineages. Kidney Int. 2013 Nov;84(5):1041-6
• All: 7 reference(s)