Tert^tm1Bvsm
Targeted Allele Detail

Summary

• Symbol: Tert^tm1Bvsm
• Name: telomerase reverse transcriptase; targeted mutation 1, Beverly S Mitchell
• MGI ID: MGI:5825476
• Synonyms: Tert^LSL
• Gene: Tert Location: Chr13:73775030-73797962 bp, + strand Genetic Position: Chr13, 40.12 cM
• Alliance: Tert^tm1Bvsm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238315
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Null/knockout)
• Mutation: Insertion
• A floxed STOP cassette inserted into exon 2. Removal of the cassette restores expression. (J:238315)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tert Mutation: 55 strains or lines available

References

• Original: J:238315 Raval A, et al., Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice. PLoS One. 2015;10(7):e0131722
• All: 1 reference(s)