Vps33b^tm1Zhen
Targeted Allele Detail

Summary

• Symbol: Vps33b^tm1Zhen
• Name: vacuolar protein sorting 33B; targeted mutation 1, Zhenyu Li
• MGI ID: MGI:5825314
• Gene: Vps33b Location: Chr7:79919369-79941323 bp, + strand Genetic Position: Chr7, 45.59 cM
• Alliance: Vps33b^tm1Zhen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:239048
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted into intron 1 and a loxP site flanked neomycin resistance gene cassette into intron 3. This creates a conditional ready allele with exons 2 and 3 floxed. (J:239048)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Vps33b Mutation: 31 strains or lines available

References

• Original: J:239048 Xiang B, et al., Characterization of a Novel Integrin Binding Protein, VPS33B, Which Is Important for Platelet Activation and In Vivo Thrombosis and Hemostasis. Circulation. 2015 Dec 15;132(24):2334-44
• All: 1 reference(s)