Pcdh9^tm1Mjhk
Targeted Allele Detail

Summary

• Symbol: Pcdh9^tm1Mjhk
• Name: protocadherin 9; targeted mutation 1, Martien J Kas
• MGI ID: MGI:5825237
• Synonyms: Pcdh9²
• Gene: Pcdh9 Location: Chr14:93250846-94128115 bp, - strand Genetic Position: Chr14, 45.8 cM
• Alliance: Pcdh9^tm1Mjhk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:237757
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neomcyin resistance cassette replaced second exon. Western blot analysis confirmed the absence of protein expression. (J:237757)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcdh9 Mutation: 63 strains or lines available

References

• Original: J:237757 Bruining H, et al., Genetic Mapping in Mice Reveals the Involvement of Pcdh9 in Long-Term Social and Object Recognition and Sensorimotor Development. Biol Psychiatry. 2015 Oct 01;78(7):485-95
• All: 2 reference(s)