Cacna1e^em1Mluo
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cacna1e^em1Mluo
• Name: calcium channel, voltage-dependent, R type, alpha 1E subunit; endonuclease-mediated mutation 1, Minmin Luo
• MGI ID: MGI:5825049
• Synonyms: Cav2.3-null
• Gene: Cacna1e Location: Chr1:154266477-154760247 bp, - strand Genetic Position: Chr1, 66.14 cM
• Alliance: Cacna1e^em1Mluo page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR/Cas9 mediated mutagenesis created frameshift mutation in exon 7. (J:234632)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cacna1e Mutation: 102 strains or lines available

References

• Original: J:234632 Zhang J, et al., Presynaptic Excitation via GABAB Receptors in Habenula Cholinergic Neurons Regulates Fear Memory Expression. Cell. 2016 Jul 28;166(3):716-28
• All: 1 reference(s)